The host complement system and arbovirus pathogenesis.
Curr Drug Targets
; 9(2): 165-72, 2008 Feb.
Article
en En
| MEDLINE
| ID: mdl-18288968
ABSTRACT
Arthropod-borne viruses (arboviruses) are a significant cause of human diseases worldwide. Interactions between these viruses and the innate immune system play a major role in determining the outcome of disease. The complement system is particularly important in this process as activation of complement can contribute to both host defense as well as injury to host tissues. This review focuses on the increasing evidence that the complement system plays key roles in both protective and pathologic outcomes of arbovirus infection.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Infecciones por Arbovirus
/
Arbovirus
/
Activación de Complemento
Tipo de estudio:
Etiology_studies
Límite:
Humans
Idioma:
En
Revista:
Curr Drug Targets
Asunto de la revista:
TERAPIA POR MEDICAMENTOS
Año:
2008
Tipo del documento:
Article
País de afiliación:
Estados Unidos