[Entrapment of herbal extracts in biodegradable microcapsules].
Biomed Khim
; 53(6): 662-71, 2007.
Article
en Ru
| MEDLINE
| ID: mdl-18323151
ABSTRACT
The microcapsules with entrapped herbal water-soluble extracts Plantago major and Calendula officinalis L. (HE) were prepared by LbL-adsorption of carrageenan and modificated chitosan onto CaCO3 microparticles with their subsequent dissolving after the treatment of EDTA. Entrapment of HE was performed by adsorption and co-precipitation techniques. The co-precipitation provided better entrapment of HE compared to adsorption. In vitro release kinetics in an artificial gastric juice (AGJ) was studied. The HE release was shown to accelerate gastric ulcer treatment in a rat model.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Plantago
/
Úlcera Gástrica
/
Cápsulas
/
Extractos Vegetales
/
Calendula
Límite:
Animals
Idioma:
Ru
Revista:
Biomed Khim
Año:
2007
Tipo del documento:
Article