[Tacrolimus in diseases other than atopic dermatitis]. / Tacrolimus en enfermedades diferentes a la dermatitis atópica.
Actas Dermosifiliogr
; 99 Suppl 2: 26-35, 2008 Feb.
Article
en Es
| MEDLINE
| ID: mdl-18346427
ABSTRACT
Topical tacrolimus is an immunosuppressant that acts through the inhibition of calcineurin and thus of the T cells. This causes a decrease in the production of interleukins, the granulocyte colony stimulating factor, alpha interferon and tumor necrosis factor. Although the use of topical tacrolimus is only indicated for the treatment of moderate or severe atopic dermatitis, its immunosuppressant effect and fewer side effects regarding topical corticosteroids have lead to the increase of its use in other types of inflammatory skin diseases. The purpose of this article is to review the use of tacrolimus in this group of diseases other than atopic dermatitis, this use not being authorized within the data sheet of the drug.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Enfermedades de la Piel
/
Tacrolimus
/
Inmunosupresores
Tipo de estudio:
Clinical_trials
Límite:
Adult
/
Child
/
Humans
Idioma:
Es
Revista:
Actas Dermosifiliogr
Año:
2008
Tipo del documento:
Article