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[Stimulation of calcium intake by growth-hormone-releasing-hormone in GH3 cells]. / Stimulation de l'entrée de calcium par le Growth-Hormone-Releasing-Hormone dans les cellules GH3.
Bresson, L; Fahmi, M; Sartor, P; Mariot, P; Dufy-Barbe, L.
Afiliación
  • Bresson L; Laboratoire de Neurophysiologie, CNRS URA 1200, Université de Bordeaux II.
C R Seances Soc Biol Fil ; 185(4): 218-23, 1991.
Article en Fr | MEDLINE | ID: mdl-1836417
The effect of GH-RH in the intra-cytosolic free Ca2+ concentration was studied in GH3 cells. To this end, we have used microspectrofluorimetry performed on single cells. We show that 60% of cells respond to a brief application of 100 nM GH-RH by an increase of their [Ca2+]i (mean increase 100% over basal values). This response which is blocked by calcium channel inhibitors results from an increased influx of Ca2+ ions from the external medium.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Hipofisarias / Calcio / Hormona Liberadora de Hormona del Crecimiento Límite: Animals Idioma: Fr Revista: C R Seances Soc Biol Fil Año: 1991 Tipo del documento: Article Pais de publicación: Francia
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Hipofisarias / Calcio / Hormona Liberadora de Hormona del Crecimiento Límite: Animals Idioma: Fr Revista: C R Seances Soc Biol Fil Año: 1991 Tipo del documento: Article Pais de publicación: Francia