Rapid analysis of L-dopa in urine samples using gold nanoelectrode ensembles.
Talanta
; 74(2): 229-34, 2007 Nov 30.
Article
en En
| MEDLINE
| ID: mdl-18371634
ABSTRACT
This work describes the application of a three-dimensional gold nanoelectrode ensembles (GNEE) for monitoring L-dopa in standards and human urine samples using flow injection analysis (FIA) with amperometric detection. Analytical results reveal that the GNEE exhibited better electrocatalytic activity than a gold disk or glassy carbon electrode. Under optimal conditions of L-dopa analysis at GNEE, the calibration plot has a linear range of 5-300 ng/mL with a coefficient of variation (CV) of 3.1% in pH 7.0 phosphate buffer saline (PBS, pH 7.0). The detection limit was 3.0 ng/mL for FIA. The high precision and sensitivity of GNEE provides a feasible means of directly determining l-dopa in urine samples.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Levodopa
/
Nanoestructuras
/
Oro
Tipo de estudio:
Diagnostic_studies
Límite:
Humans
Idioma:
En
Revista:
Talanta
Año:
2007
Tipo del documento:
Article
País de afiliación:
Taiwán