Voxel-based morphometry study on brain structure in children with high-functioning autism.
Neuroreport
; 19(9): 921-5, 2008 Jun 11.
Article
en En
| MEDLINE
| ID: mdl-18520994
ABSTRACT
Earlier studies have suggested abnormal brain volumes in autism, but inconsistencies exist. Using voxel-based morphometry, we compared global and regional brain volumes in 17 high-functioning autistic children with 15 matched controls. We identified significant reduction in left white matter volume and white/gray matter ratio in autism. Regional brain volume reductions were detected for right anterior cingulate, left superior parietal lobule white matter volumes, and right parahippocampal gyrus gray matter volume, whereas enlargements in bilateral supramarginal gyrus, right postcentral gyrus, right medial frontal gyrus, and right posterior lobe of cerebellum gray matter in autism. Our findings showed global and regional brain volumes abnormality in high-functioning autism.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Trastorno Autístico
/
Encéfalo
/
Mapeo Encefálico
/
Imagen por Resonancia Magnética
Tipo de estudio:
Prognostic_studies
Límite:
Adolescent
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Child
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Female
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Humans
/
Male
Idioma:
En
Revista:
Neuroreport
Asunto de la revista:
NEUROLOGIA
Año:
2008
Tipo del documento:
Article
País de afiliación:
China