Fatal intoxication with milnacipran.
J Forensic Leg Med
; 15(6): 388-90, 2008 Aug.
Article
en En
| MEDLINE
| ID: mdl-18586210
ABSTRACT
The antidepressant milnacipran is a double serotonin/noradrenalin reuptake inhibitor. The low reported incidence of intoxication indicates excellent tolerance in comparison with tricyclic and second generation antidepressants. We report a fatal intoxication associating milnacipran, at blood levels (femoral=21.5 mg/l, cardiac=20 mg/l) 40-fold higher than the usual treatment concentration, and six other molecules (fluoxetine, norfluoxetine, sertraline, cyamemazine, nordazepam and oxazepam) at therapeutic levels. To the best of our knowledge, this is the first reported fatal intoxication involving milnacipran.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Ciclopropanos
/
Antidepresivos
Límite:
Adult
/
Female
/
Humans
Idioma:
En
Revista:
J Forensic Leg Med
Asunto de la revista:
JURISPRUDENCIA
Año:
2008
Tipo del documento:
Article
País de afiliación:
Francia