Muscle weakness in a girl with autoimmune hepatitis and Graves' disease.
Eur J Pediatr
; 168(2): 241-3, 2009 Feb.
Article
en En
| MEDLINE
| ID: mdl-18604559
ABSTRACT
Autoimmune hepatitis (AIH) is a chronic hepatic autoimmune disease of unknown etiology associated with inflammatory changes and autoantibodies. The combination of AIH, Grave's disease, and myasthenia gravis (MG) is rare, with only one other case reported. We report a pediatric patient with AIH type 2 and Grave's disease who developed MG whilst on a treatment with corticosteroids. A 13-year-old girl, diagnosed with thyrotoxicosis, was identified as having AIH type 2. During the course of her therapy, she developed muscle weakness. Investigations revealed increased anti-acetylcholine receptor (AChR) antibodies and her electromyography (EMG) was characteristic for MG. Her course is described here. This case highlights the importance of investigating muscle weakness in severely ill hospitalized patients.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Enfermedad de Graves
/
Debilidad Muscular
/
Hepatitis Autoinmune
/
Miastenia Gravis
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Female
/
Humans
Idioma:
En
Revista:
Eur J Pediatr
Año:
2009
Tipo del documento:
Article
País de afiliación:
Canadá