Crisp proteins and sperm chemotaxis: discovery in amphibians and explorations in mammals.
Int J Dev Biol
; 52(5-6): 489-501, 2008.
Article
en En
| MEDLINE
| ID: mdl-18649262
ABSTRACT
Crisp proteins appear to play multiple roles in the life history of sperm. One of these roles is to act as a sperm chemoattractant. Allurin, a 21 kDa Crisp protein rapidly released from the egg jelly of at least two frogs, X. laevis and X. tropicalis, elicits directed motility in both homospecific and heterospecific sperm. In X. tropicalis, allurin is coded for by the newly documented Crisp A gene. Recently, the observation that allurin can also elicit chemotaxis in mouse sperm raises the question of whether allurin-like proteins might act as sperm chemoattractants in mammals. Although an allurin gene has yet to be documented in mammals, Crisp proteins truncated post-translationally appear to exist in both the male and female reproductive tract of mammals.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Espermatozoides
/
Proteínas Portadoras
/
Proteínas del Huevo
/
Quimiotaxis
Tipo de estudio:
Prognostic_studies
Límite:
Animals
Idioma:
En
Revista:
Int J Dev Biol
Asunto de la revista:
BIOLOGIA
/
EMBRIOLOGIA
Año:
2008
Tipo del documento:
Article
País de afiliación:
Estados Unidos
Pais de publicación:
ES
/
ESPANHA
/
ESPAÑA
/
SPAIN