[Familial adult cystic kidneys and malignant teratomas after kidney transplantation with cyclosporin therapy]. / Familiäre adulte Zystennieren und maligne Teratome nach Nierentransplantation unter Ciclosporintherapie.

We report on two brothers with adult polycystic kidney disease, malignant teratomas and other genital malformations. Because of the unusual accumulation of malformations of embryologically related organs, we postulate a connection between malformations of the kidneys and the genital tract, on the one hand, and teratomas on the other. No genetic coherence is known so far. It is unlikely that immunosuppression with cyclosporin after transplantation had caused these tumours.