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Cisplatin-associated thrombosis.
Jafri, Mariam; Protheroe, Andrew.
Afiliación
  • Jafri M; Department of Medical Oncology, Oxford University, Churchill Hospital, Oxford, UK. mariamjafri@hotmail.com
Anticancer Drugs ; 19(9): 927-9, 2008 Oct.
Article en En | MEDLINE | ID: mdl-18766008
The discovery of cisplatin has made arguably the biggest contribution to cancer medicine, providing the basis for the chemotherapy treatment of many malignancies. In addition to well-documented toxicities such as neurotoxicity, cisplatin-induced vascular toxicity is becoming an increasing concern, with some authors describing it in up to 12% of patients. Given the efficacy of cisplatin, vascular toxicity represents a significant survivorship issue. We describe different manifestations of cisplatin-associated thrombosis and its putative pathophysiology.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trombosis / Cisplatino / Neoplasias de Células Germinales y Embrionarias Tipo de estudio: Risk_factors_studies Límite: Adult / Humans / Male Idioma: En Revista: Anticancer Drugs Asunto de la revista: ANTINEOPLASICOS Año: 2008 Tipo del documento: Article Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trombosis / Cisplatino / Neoplasias de Células Germinales y Embrionarias Tipo de estudio: Risk_factors_studies Límite: Adult / Humans / Male Idioma: En Revista: Anticancer Drugs Asunto de la revista: ANTINEOPLASICOS Año: 2008 Tipo del documento: Article Pais de publicación: Reino Unido