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Idiopathic arterial medial calcification of the thoracic arteries in an adult horse.
Fales-Williams, Amanda; Sponseller, Beatrice; Flaherty, Heather.
Afiliación
  • Fales-Williams A; Department of Veterinary Pathology, College of Veterinary Medicine, Iowa State University, Ames, Iowa 50011-1250, USA. afales@iastate.edu
J Vet Diagn Invest ; 20(5): 692-7, 2008 Sep.
Article en En | MEDLINE | ID: mdl-18776115
A 6-year-old, gelded, Paint horse displayed clinical signs of muscle wasting and limb stiffness for a 6-month period. The horse's clinical signs abated with corticosteroid therapy, but returned upon cessation of treatment. Upon necropsy, severe lesions of aortic thickening and aortic valve rigidity were observed. Histologically, the tunica media of the aorta, coronary arteries, and pulmonary arteries were expanded by foci of elastin fiber calcification and extracellular matrix with lacunae formation. The vascular lesions are comparative to what has been described as medial arterial calcification, seen in humans suffering from chronic renal failure or diabetes mellitus. No exposure to vitamin D-containing plants or feedstuff could be documented at the time of onset or during the period of clinical signs. The current case describes dramatic lesions of arterial medial calcification of the aorta, coronary, and pulmonary arteries of undetermined cause.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Arterias Torácicas / Calcinosis / Enfermedades de los Caballos Límite: Animals Idioma: En Revista: J Vet Diagn Invest Asunto de la revista: MEDICINA VETERINARIA Año: 2008 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Arterias Torácicas / Calcinosis / Enfermedades de los Caballos Límite: Animals Idioma: En Revista: J Vet Diagn Invest Asunto de la revista: MEDICINA VETERINARIA Año: 2008 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos