Performance of a 3-bladed propeller pump to provide cavopulmonary assist in the failing Fontan circulation.
Ann Thorac Surg
; 86(4): 1343-7, 2008 Oct.
Article
en En
| MEDLINE
| ID: mdl-18805191
ABSTRACT
PURPOSE:
We hypothesized that a propeller pump design would function optimally to provide cavopulmonary assist in a univentricular Fontan circulation. DESCRIPTION The hydraulic and hemolysis performance of a rigid three-bladed propeller prototype (similar to a folding propeller design) was characterized. Pressure and flow measurements were taken for flow rates of 0.5 to 3 liters per minute (LPM) for 5,000 to 7,000 revolutions per minute (RPM) using a blood analog fluid. Hemolysis testing was performed using fresh bovine blood for 2 LPM at 6,000 RPM for a 6-hour duration. EVALUATION The prototype performed well over the design operating range by producing a pressure rise of 5 to 50 mm Hg. Plasma free hemoglobin concentration remained less than 15 mg/dL. The normalized index of hemolysis peaked during the first hour, and then remained less than 10 mg/dL thereafter.CONCLUSIONS:
A propeller pump has the pressure-flow characteristics and minimal risk of hemolysis and venous pathway obstruction which make it ideal for temporary cavopulmonary assist. This type of device has the potential to provide a new therapeutic option for patients with failing univentricular Fontan physiology as a bridge-to-recovery or transplantation.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Circulación Asistida
/
Procedimiento de Fontan
/
Cuidados Intraoperatorios
Tipo de estudio:
Diagnostic_studies
/
Health_technology_assessment
Límite:
Humans
Idioma:
En
Revista:
Ann Thorac Surg
Año:
2008
Tipo del documento:
Article
País de afiliación:
Estados Unidos