The newborn with seizures -- a follow-up study.
Indian Pediatr
; 45(9): 749-52, 2008 Sep.
Article
en En
| MEDLINE
| ID: mdl-18820381
ABSTRACT
OBJECTIVE:
To determine the sequelae of neonatal seizures in a cohort of newborns, recruited over a six month period.DESIGN:
Prospective hospital based study.SETTING:
The neonatal intensive care unit (NICU) of a tertiary care hospital.PARTICIPANTS:
135 babies were recruited of whom 10 died and 25 were lost to follow up.METHODS:
The cases were followed up over four months.RESULTS:
68% of the babies followed up were normal; 32% had an abnormal neurological outcome. Seven (7%) developed post-neonatal epilepsy. Hypocalcemia was significantly associated with mortality (OR 21.9; 95% CI 1.2-391.2). No risk factors could be identified for post neonatal epilepsy. Presence of spike waves in the EEG was significantly related to abnormal neurological outcome (OR 3.5; 95% C.I. 1.2-10.8).CONCLUSIONS:
Majority of neonates with seizures have a normal outcome with no developmental delay or neurological deficit. Predominantly spike waves in the EEG is predictive of abnormal neurological outcome.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Convulsiones
/
Discapacidades del Desarrollo
/
Epilepsia
/
Enfermedades del Sistema Nervioso
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Prognostic_studies
Límite:
Humans
/
Newborn
País/Región como asunto:
Asia
Idioma:
En
Revista:
Indian Pediatr
Año:
2008
Tipo del documento:
Article
País de afiliación:
India