Hepoxilin A3 induces heat shock protein (HSP72) expression in human neutrophils.
Biochem Biophys Res Commun
; 179(1): 52-6, 1991 Aug 30.
Article
en En
| MEDLINE
| ID: mdl-1883378
ABSTRACT
In this paper we show that hepoxilin A3 induces the expression of heat shock protein expression in human neutrophils at a concentration of 100 nM using Western blotting techniques employing the use of a commercial monoclonal antibody to HSP72. No regiospecificity was observed as the 8S enantiomer of HxA3 was as active as the 8R enantiomer of HxA3. Comparison of the effects of HxA3 with 12S-HETE and PGA1 indicated that HxA3 was as effective as 12S-HETE although PGA1 was essentially inactive at the same concentration used for these 12-lipoxygenase products.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Ácido 8,11,14-Eicosatrienoico
/
Proteínas de Choque Térmico
/
Neutrófilos
Límite:
Humans
Idioma:
En
Revista:
Biochem Biophys Res Commun
Año:
1991
Tipo del documento:
Article
País de afiliación:
Canadá