[Diffusion properties of water in the human crystalline lens during cataract development]. / Diffuzionnye svoistva vody v khrustalike cheloveka pri razvitii katarakty.
Biofizika
; 36(2): 327-9, 1991.
Article
en Ru
| MEDLINE
| ID: mdl-1892908
ABSTRACT
Normal and cataractal decapsulated lenses of man were studied by NMR method-spin echo to obtain information concerning efficient coefficients of self diffusion, times of spin-spin relaxation of water protons (T2) and water content in the lens (c) at 25 degrees C in the course of cataractogenesis. It has been found that the values T2 and c at 25 degrees C are much higher in the nuclei of completely turbid lenses than in the transparent ones; the self-diffusion coefficients in the turbid lenses were also higher. At -9 degrees C a significant decrease of the content of undestroyed by frost (bound) water was observed at the stage of mature cataract as compared to transparent lenses. It is suggested that the most specific differences between the nuclei of transparent and completely turbid lenses are related to increased diffusion mobility of water molecules, apparently, at the expense of damaged plasmic membranes of the lens fibres noted during cataract development.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Catarata
/
Agua
/
Difusión
/
Cristalino
Límite:
Humans
Idioma:
Ru
Revista:
Biofizika
Año:
1991
Tipo del documento:
Article