Improving parenchyma segmentation by simultaneous estimation of tissue property T1 map and group-wise registration of inversion recovery MR breast images.
Med Image Comput Comput Assist Interv
; 11(Pt 1): 342-50, 2008.
Article
en En
| MEDLINE
| ID: mdl-18979765
ABSTRACT
The parenchyma tissue in the breast has a strong relation with predictive biomarkers of breast cancer. To better segment parenchyma, we perform segmentation on estimated tissue property T1 map. To improve the estimation of tissue property (T1) which is the basis for parenchyma segmentation, we present an integrated algorithm for simultaneous T1 map estimation, T1 map based parenchyma segmentation and group-wise registration on series of inversion recovery magnetic resonance (MR) breast images. The advantage of using this integrated algorithm is that the simultaneous T1 map estimation (E-step) and group-wise registration (R-step) could benefit each other and jointly improve parenchyma segmentation. In particular, in E-step, T1 map based segmentation could help perform an edge-preserving smoothing on the tentatively estimated noisy T1 map, and could also help provide tissue probability maps to be robustly registered in R-step. Meanwhile, the improved estimation of T1 map could help segment parenchyma in a more accurate way. In R-step, for robust registration, the group-wise registration is performed on the tissue probability maps produced in E-step, rather than the original inversion recovery MR images, since tissue probability maps are the intrinsic tissue property which is invariant to the use of different imaging parameters. The better alignment of images achieved in R-step can help improve T1 map estimation and indirectly the T1 map based parenchyma segmentation. By iteratively performing E-step and R-step, we can simultaneously obtain better results for T1 map estimation, T1 map based segmentation, group-wise registration, and finally parenchyma segmentation.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Algoritmos
/
Mama
/
Neoplasias de la Mama
/
Reconocimiento de Normas Patrones Automatizadas
/
Inteligencia Artificial
/
Imagen por Resonancia Magnética
/
Interpretación de Imagen Asistida por Computador
/
Aumento de la Imagen
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Female
/
Humans
Idioma:
En
Revista:
Med Image Comput Comput Assist Interv
Asunto de la revista:
DIAGNOSTICO POR IMAGEM
/
INFORMATICA MEDICA
Año:
2008
Tipo del documento:
Article
País de afiliación:
Estados Unidos
Pais de publicación:
ALEMANHA
/
ALEMANIA
/
DE
/
DEUSTCHLAND
/
GERMANY