Variation of angle parameters in asians: an anterior segment optical coherence tomography study in a population of singapore malays.
Invest Ophthalmol Vis Sci
; 50(6): 2626-31, 2009 Jun.
Article
en En
| MEDLINE
| ID: mdl-19182259
PURPOSE: To assess variations in angle parameters using anterior segment optical coherence tomography (AS-OCT) and to investigate demographic, ocular and systemic associations of angle width. METHODS: This was a substudy of a population based, cross-sectional survey of 3280 (78.7% response rate) Malay people aged 40 to 80 years in Singapore. All participants underwent a standardized interview and ocular and systemic examination. AS-OCT was performed on 291 consecutive patients in standardized dark conditions. Angle opening distance (AOD-500) and trabecular-iris space area (TISA-500) 500 microm from the scleral spur were determined for the nasal and temporal angles. Anterior chamber depth (ACD) was also measured. RESULTS: AS-OCT measurements were analyzed in 239 (82.1%) right eyes. Mean AOD 500 was smaller in women than in men, both nasally (0.255 vs. 0.293 mm, P = 0.026) and temporally (0.245 vs. 0.286 mm, P = 0.023). Mean TISA-500 was smaller in women in the nasal quadrant only (0.104 vs. 0.117 mm, P = 0.035). Mean ACD was smaller in women than in men (2.71 vs. 2.87 mm, P = 0.001). Multiple linear regression showed that axial length and ACD were significantly associated with AOD-500 and TISA-500 both nasally (adjusted R(2) = 0.34 for AOD-500 and 0.20 for TISA-500) and temporally (adjusted R(2) = 0.35 for AOD-500 and 0.24 for TISA-500). Body mass index, HbA(1c), systolic blood pressure, intraocular pressure, cup-to-disc ratio, and central corneal thickness were not significantly associated with AOD-500, TISA-500, or ACD. CONCLUSIONS: In this Malay population, angle width measured by AS-OCT was smaller in women than in men, and in eyes with shorter axial length and shallower ACD.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Tomografía de Coherencia Óptica
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Pueblo Asiatico
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Segmento Anterior del Ojo
Tipo de estudio:
Observational_studies
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Prevalence_studies
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Risk_factors_studies
Límite:
Adult
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Aged
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Aged80
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Female
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Humans
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Male
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Middle aged
País/Región como asunto:
Asia
Idioma:
En
Revista:
Invest Ophthalmol Vis Sci
Año:
2009
Tipo del documento:
Article
País de afiliación:
Singapur
Pais de publicación:
Estados Unidos