Anticoagulant activity and platelet aggregation in blood plasma from rats after intranasal administration of adenosine triphosphate and its complex with heparin.
Bull Exp Biol Med
; 146(3): 273-5, 2008 Sep.
Article
en En
| MEDLINE
| ID: mdl-19240836
ABSTRACT
Fourfold intranasal administration of ATP was followed by an increase in anticoagulant activity and decrease in platelet aggregation in blood plasma of healthy rats and, particularly, of animals with suppressed function of the anticoagulant system. These changes decrease the risk of the prethrombotic state. Complex of ATP and high-molecular-weight heparin decreased platelet aggregation only in the blood from healthy animals, but increased anticoagulant potential of plasma hemostasis in prethrombotic animals.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Coagulación Sanguínea
/
Heparina
/
Adenosina Trifosfato
/
Agregación Plaquetaria
/
Anticoagulantes
Límite:
Animals
Idioma:
En
Revista:
Bull Exp Biol Med
Año:
2008
Tipo del documento:
Article
País de afiliación:
Rusia
Pais de publicación:
EEUU
/
ESTADOS UNIDOS
/
ESTADOS UNIDOS DA AMERICA
/
EUA
/
UNITED STATES
/
UNITED STATES OF AMERICA
/
US
/
USA