Fetal cerebral ventricular pointing as a marker of spina bifida: incidence and observational agreement.
J Ultrasound Med
; 28(3): 317-20, 2009 Mar.
Article
en En
| MEDLINE
| ID: mdl-19244067
ABSTRACT
OBJECTIVE:
Occipital cerebral ventricular pointing is a promising intracranial marker for spina bifida. We sought to determine (1) the incidence of pointing in fetuses with and without spina bifida and (2) inter-observer and intraobserver agreement for visualizing pointing.METHODS:
Second-trimester transverse axial images of the lateral cerebral ventricles from an equal number of affected and unaffected fetuses were independently reviewed in a blinded fashion by 2 examiners.RESULTS:
Sixty-two fetuses (31 with isolated spina bifida and 31 without) had sonographic examinations at 19.2+/-1.3 weeks (mean+/-SD). Pointing was present in 77.3% of fetuses with spina bifida and 15% of those without by the first examiner and in 78.3% of fetuses with spina bifida and 10% of those without by the second examiner. Interobserver and intraobserver agreement were substantial (kappa=0.69 and 0.78, respectively).CONCLUSIONS:
Ventricular pointing is a highly agreed-on finding that is substantially associated with but not pathognomonic for fetal spina bifida.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Ecoencefalografía
/
Ventrículos Cerebrales
/
Disrafia Espinal
/
Ultrasonografía Prenatal
/
Medición de Riesgo
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
/
Incidence_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Female
/
Humans
/
Male
País/Región como asunto:
America do norte
Idioma:
En
Revista:
J Ultrasound Med
Año:
2009
Tipo del documento:
Article
País de afiliación:
Estados Unidos