[Glucose metabolism alterations and follow-up study of a non-diabetic adult population]. / Alteraciones del metabolismo de la glucosa y estudio de seguimiento de una población adulta no diabética.
Rev Clin Esp
; 209(1): 3-8, 2009 Jan.
Article
en Es
| MEDLINE
| ID: mdl-19268090
ABSTRACT
OBJECTIVE:
To determine the appearance of type 2 diabetes mellitus (DM2) and impaired fasting glucose (IFG) at five years of follow-up in a known non-diabetic population.DESIGN:
nested case control studies (case s-control into a cohort) developed in two stages 1) identification and characterization of the cohort and 2) follow-up. STUDY POPULATION representative sample of a non-diabetic population between 40 and 75 years old attended in a Primary Health Center. IDENTIFICATION 326 persons, 2.1% of whom were diagnosed of previously unknown DM2 and 7.3% of IFG. Insulin resistance (IR) was higher in patients with IFG and pancreatic function of beta cells (PFBC) was higher in the population without glucose metabolism alteration. FOLLOW-UP 121 persons, 9.7 % of whom evolved to DM2 (all with IFG). IFG proportion at the end of the follow-up was 23.96%.CONCLUSIONS:
At 5 years of follow-up, more than 1/3 of the population studied developed DM2 or IFG. These diagnoses were related with IR and PFBC.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Trastornos del Metabolismo de la Glucosa
/
Diabetes Mellitus
Tipo de estudio:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Es
Revista:
Rev Clin Esp
Asunto de la revista:
MEDICINA
Año:
2009
Tipo del documento:
Article
Pais de publicación:
ES
/
ESPANHA
/
ESPAÑA
/
SPAIN