Dietary fiber and fiber-rich food intake in relation to risk of stroke in male smokers.
Eur J Clin Nutr
; 63(8): 1016-24, 2009 Aug.
Article
en En
| MEDLINE
| ID: mdl-19319150
ABSTRACT
BACKGROUND/OBJECTIVES:
There is convincing evidence that a high dietary fiber intake may lower the risk of coronary heart disease. However, the role of fiber in the prevention of stroke is unclear. We examined the associations of dietary fiber and fiber-rich food intake with risk of stroke within the Alpha-tocopherol, Beta-carotene Cancer Prevention Study. SUBJECTS/METHODS:
Between 1985 and 1988, 26,556 Finnish male smokers aged 50-69 years, who had no history of stroke, completed a dietary questionnaire. During a mean follow-up of 13.6 years, 2702 cerebral infarctions, 383 intracerebral hemorrhages and 196 subarachnoid hemorrhages were ascertained.RESULTS:
After adjustment for cardiovascular risk factors and folate and magnesium intakes, there was no significant association between intake of total fiber, water-soluble fiber, water-insoluble fiber, or fiber derived from fruit or cereal sources and risk of any stroke subtype. Vegetable fiber intake, as well as the consumption of fruit, vegetables and cereals, was inversely associated with the risk of cerebral infarction; the multivariate relative risks for the highest quintile of intake as compared with the lowest were 0.86 (95% confidence interval (CI) 0.76-0.99) for vegetable fiber, 0.82 (95% CI 0.73-0.93) for fruit, 0.75 (95% CI 0.66-0.85) for vegetables and 0.87 (95% CI 0.74-1.03) for cereals. Vegetable consumption was inversely associated with risk of subarachnoid hemorrhage (relative risk for highest versus lowest quintile 0.62; 95% CI 0.40-0.98), and cereal consumption was inversely associated with risk of intracerebral hemorrhage (relative risk 0.64; 95% CI 0.41-1.01).CONCLUSIONS:
These findings suggest a beneficial effect of the consumption of fruits, vegetables and cereals on stroke risk.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Fibras de la Dieta
/
Accidente Cerebrovascular
/
Dieta
Tipo de estudio:
Etiology_studies
/
Risk_factors_studies
Límite:
Humans
/
Male
/
Middle aged
País/Región como asunto:
Europa
Idioma:
En
Revista:
Eur J Clin Nutr
Asunto de la revista:
CIENCIAS DA NUTRICAO
Año:
2009
Tipo del documento:
Article
País de afiliación:
Suecia