Introduction of an individually optimized protocol for the injection of contrast medium for coronary CT angiography.
Eur Radiol
; 19(10): 2373-82, 2009 Oct.
Article
en En
| MEDLINE
| ID: mdl-19424699
ABSTRACT
The aim of this study was to determine whether individually tailored protocols for the injection of contrast medium (CM) result in higher and more homogeneous vascular attenuation throughout the coronary arteries at coronary CT angiography compared with conventional injection protocols using fixed injection parameters. Of 120 patients included in the study, 80 patients were randomized into two groups. Group 1 received 80 mL of CM at 6 mL/s. For group 2 injection parameters were individually adjusted to patient weight, the duration of CT data acquisition, and attenuation parameters following a test bolus. In the control group (group 3) the volume of CM was adjusted to the duration of CT data acquisition and injected at 5 mL/s. Attenuation was measured in the proximal, middle, and distal right coronary artery (RCA), in the proximal and middle left anterior descending artery (LAD), and in cranial and caudal sections of both ventricles. Patient parameters, scan delay, and scan duration did not differ significantly between the groups. Mean CM volume was 82.5 mL (flow rate 5.1 mL/s) in group 2 and 73.5 mL in group 3. Attenuation in both RCA and LAD was significantly higher for group 2 vs. group 3 (RCA 414.9 + or - 49.9)-396.1(+ or - 52.1) HU vs. 366.0(+ or - 64.3)-341.6(+ or - 72.5) HU; LAD 398.9(+ or - 48.6)-364.6(+ or - 44.6) HU vs. 356.3(+ or - 69.5)-323.0(+ or - 67.2) HU). For group 1 vs. group 2 only attenuation in the distal RCA differed significantly 396.1(+ or - 52.1) vs. 370.7(+ or - 70.5) HU. Individually tailored CM injection protocols yield higher attenuation, especially in the distal segments of the coronary vessels, compared with injection protocols using fixed injection parameters.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Enfermedad de la Arteria Coronaria
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Yohexol
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Intensificación de Imagen Radiográfica
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Tomografía Computarizada por Rayos X
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Medios de Contraste
Tipo de estudio:
Clinical_trials
/
Diagnostic_studies
Límite:
Female
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Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Eur Radiol
Asunto de la revista:
RADIOLOGIA
Año:
2009
Tipo del documento:
Article
País de afiliación:
Alemania