[Primary plasma cell leukemia associated with hypercalcemia].
Rinsho Ketsueki
; 32(8): 879-83, 1991 Aug.
Article
en Ja
| MEDLINE
| ID: mdl-1942529
ABSTRACT
A 34-year-old male was admitted to our hospital because of anorexia and nausea in September, 1987. On admission, anemia, thrombocytopenia and hypercalcemia were observed, and the peripheral blood showed leukocytosis with atypical plasma cells (50%). Bone marrow aspiration showed hypercellularity, with a presence of atypical plasma cells (82%). The M-type protein in the serum and urine was identified as lambda Bence Jones protein by immunoelectrophoresis. On systemic skeletal X-rays, osteolytic lesions were not detected. Thus, a diagnosis of plasma cell leukemia associated with hypercalcemia was made. Hypercalcemia was treated successfully with overhydration. However the disease was refractory to combination chemotherapy, and at 10 months after diagnosis, he died of septic candidiasis. Hypercalcemia associated with plasma cell leukemia in its initial stage is rare.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Leucemia de Células Plasmáticas
/
Hipercalcemia
Tipo de estudio:
Prognostic_studies
/
Risk_factors_studies
Límite:
Adult
/
Humans
/
Male
Idioma:
Ja
Revista:
Rinsho Ketsueki
Año:
1991
Tipo del documento:
Article