[Effects of beta 1-adrenoblocker bisoprolol on endothelial dysfunction in patients with stable angina pectoris in combination with chronic obstructive pulmonary disease].
Ter Arkh
; 81(3): 28-31, 2009.
Article
en Ru
| MEDLINE
| ID: mdl-19459418
ABSTRACT
AIM:
To study effects of a cardioselective beta-adrenoblocker bisoprolol on vascular wall endothelium and external respiration function in stable angina of effort combined with chronic obstructive pulmonary disease (COPD). MATERIAL ANDMETHODS:
Endothelial function and external respiration were studied before and after 4-week treatment with bisoprolol in 36 patients with stable angina and COPD using assessment of endothelium-dependent vasodilatation (EDVD) and concentrations of nitric oxide metabolites.RESULTS:
Significant improvement of endothelial function was achieved due to bisoprolol 4-week treatment which did not affect external respiration function.CONCLUSION:
Bisoprolol is effective and safe drug in the treatment of stable angina combined with COPD. It can noticeably improve endothelial function.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Endotelio Vascular
/
Bisoprolol
/
Antagonistas Adrenérgicos beta
/
Enfermedad Pulmonar Obstructiva Crónica
/
Angina de Pecho
Tipo de estudio:
Diagnostic_studies
Límite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Ru
Revista:
Ter Arkh
Año:
2009
Tipo del documento:
Article