Hematological changes in subperiodic Brugia malayi infection of the leaf-monkey, Presbytis cristata.
Southeast Asian J Trop Med Public Health
; 22(2): 168-70, 1991 Jun.
Article
en En
| MEDLINE
| ID: mdl-1948274
ABSTRACT
Hematological changes were monitored in the leaf-monkey, Presbytis cristata, infected experimentally with 200 subperiodic Brugia malayi infective larvae. Prepatent periods were 54-86 days and peak microfilarial geometric mean counts (GMCs) were 1324 per ml blood. Total leukocyte and differential counts were measured at pre-infection, and then at weakly intervals before and during patency. Blood eosinophil level increased to about thrice the initial level at 3 weeks post-infection and this was maintained for the next 13 weeks before it started to rise again, increasing to more than 5 times the initial level at 20 weeks post-infection. The observed pattern of eosinophilia is probably related to the level of microfilaremia and the destruction of microfilariae in the spleen. There was no significant change in the total leukocyte counts during the period of observation.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Filariasis Linfática
/
Brugia
/
Cercopithecidae
Límite:
Animals
Idioma:
En
Revista:
Southeast Asian J Trop Med Public Health
Año:
1991
Tipo del documento:
Article
País de afiliación:
Malasia