Impact of diabetes on early and mid-term survival after coronary artery bypass graft surgery in the Hong Kong Chinese population.

ABSTRACT

OBJECTIVE: To determine the impact of diabetes on early and mid-term survival in the Hong Kong Chinese population undergoing coronary artery bypass graft surgery. DESIGN: Prospective study. SETTING: Regional hospital, Hong Kong. PATIENTS A total of 904 consecutive patients following coronary artery bypass graft surgery from November 1999 to December 2003 were prospectively analysed. Among them, 377 (42%) diabetic and 527 (58%) non-diabetic patients were evaluated. MAIN OUTCOME MEASURES: Hospital mortality, mid-term mortality, and percutaneous coronary intervention-free survival. RESULTS: The diabetic group had a higher risk score than the non-diabetic group (mean+/-standard deviation EuroSCORE 4.7+/-3.4 and 3.6+/-3.4, respectively; P<0.001). Hospital mortality was 3.4% in the diabetic group compared to 2.8% in the non-diabetic group (P=0.698). Multiple logistic regression analysis identified left ventricular ejection fraction of less than 30% and preoperative intubation as independent risk factors for early hospital death. There were 81 late deaths and the actuarial survival at 48 months for the diabetic and non-diabetic patients were 86% and 90%, respectively (P=0.298). The angina-free survival and percutaneous coronary intervention-free survival at 48 months for the diabetic and non-diabetic patients yielded no statistically significant difference. CONCLUSIONS: Diabetes mellitus was not a predictor of early and mid-term mortality after coronary artery bypass graft surgery in our Chinese population. Furthermore, diabetes did not affect angina recurrence or intervention free-survival up to 4 years.