A new method for the treatment of chronic fungal meningitis: continuous infusion into the cerebrospinal fluid for coccidioidal meningitis.
Am J Med Sci
; 338(1): 79-82, 2009 Jul.
Article
en En
| MEDLINE
| ID: mdl-19506457
ABSTRACT
Coccidioidal meningitis is a lethal disease, and current therapy is not curative or is burdened with serious toxicities and logistic difficulties. In a patient with refractory disease, continuous infusion amphotericin B therapy was given via a programmable implanted pump into the cisternal subarachnoid space. The patient progressively responded, evidenced clinically and by laboratory studies. Drug delivery issues were addressed during this course that could guide future use of this modality, which is a promising novel avenue of therapy for chronic meningitis.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Bombas de Infusión Implantables
/
Anfotericina B
/
Antifúngicos
Límite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Am J Med Sci
Año:
2009
Tipo del documento:
Article
País de afiliación:
Estados Unidos