Familial incidence of C3 nephritic factor.
Nephron
; 59(2): 261-5, 1991.
Article
en En
| MEDLINE
| ID: mdl-1956487
ABSTRACT
C3 nephritic factor (NEF) has been found in 3 siblings presenting different (or none) degrees of renal disease. Other relatives, including their dead father, suffered from a renal illness. In 2 of the siblings, NEF activity was restricted to IgG1 and IgG3 subclasses. Familial NEF incidence and a shared C3 allotype and a common HLA haplotype including BfS alleles for the 3 NEF-positive siblings suggest that at least in our cases genetical factors may be involved in NEF generation.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Factor Nefrítico del Complemento 3
/
Glomerulonefritis
Tipo de estudio:
Incidence_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Nephron
Año:
1991
Tipo del documento:
Article
País de afiliación:
España