Characterization of genotypes of Enterocytozoon bieneusi in immunosuppressed and immunocompetent patient groups.
J Eukaryot Microbiol
; 56(4): 388-93, 2009.
Article
en En
| MEDLINE
| ID: mdl-19602086
ABSTRACT
A retrospective phylogenetic analysis was performed on isolates of Enterocytozoon bieneusi to characterize the genotypes in different patient cohorts. Fifty-seven isolates, collected from patients living in Malawi and the Netherlands, were classified by age and immune status of the hosts. Sequence analysis of the internal transcribed spacer (ITS) region identified 16 genotypes; nine have not previously been described. Genotypes K and D were most prevalent among patient groups, whereas genotype C was restricted to transplantation patients receiving immunosupressives and genotype B showed a predisposition toward patients living with HIV/AIDS. Different genotypes showed more dispersion among isolates from Malawi compared with those from the Netherlands. A constructed map estimating the genealogy of the ITS region reveals a dynamic evolutionary process between the genotypes.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Variación Genética
/
Microsporidiosis
/
Huésped Inmunocomprometido
/
Enterocytozoon
Límite:
Adult
/
Aged
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
/
Middle aged
País/Región como asunto:
Africa
/
Europa
Idioma:
En
Revista:
J Eukaryot Microbiol
Asunto de la revista:
MICROBIOLOGIA
/
PARASITOLOGIA
Año:
2009
Tipo del documento:
Article
País de afiliación:
Países Bajos