Mitochondrial myopathy caused by clevudine therapy in chronic hepatitis B patients.
Hepatol Res
; 39(9): 944-7, 2009 Sep.
Article
en En
| MEDLINE
| ID: mdl-19712273
ABSTRACT
As a pyrimidine analog with potent and sustained antiviral activity against hepatitis B virus, clevudine has been known to have no effect on mitochondrial structure, DNA content, or function. There is little information on the side effects of clevudine, which has not been approved for the treatment of chronic hepatitis B outside of South Korea. We report here two cases of chronic hepatitis B patients who experienced mitochondrial myopathy after clevudine medication. These cases raise concerns about the safety profile of clevudine for the treatment of chronic hepatitis B.
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1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Hepatol Res
Año:
2009
Tipo del documento:
Article