The rapid molecular genetic diagnosis of cystic fibrosis by polymerase chain reaction: an experience report.
Czech Med
; 13(4): 145-59, 1990.
Article
en En
| MEDLINE
| ID: mdl-1981984
ABSTRACT
The authors report their experience with about two thousand DNA amplifications by polymerase chain reaction (PCR) in prenatal diagnosis of cystic fibrosis. The method is demonstrated on examples of diagnostic informativity and prenatal diagnosis examination in a family at 1 in 4 risk of the disease using closely CF-linked diagnostic polymorphisms J3.11/MspI, MetH/MspI, CS7/HhaI, KM19/PstI, Mp6-d9/MspI and XV2c/TaqI, PCR methodology and safety precautions are discussed.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Diagnóstico Prenatal
/
Fibrosis Quística
/
Enfermedades Fetales
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
/
Risk_factors_studies
Límite:
Humans
Idioma:
En
Revista:
Czech Med
Año:
1990
Tipo del documento:
Article
Pais de publicación:
CZ
/
CZECH REPUBLIC
/
REPUBLICA CHECA
/
REPÚBLICA TCHECA