Precursors of endometrial and ovarian carcinoma.
Virchows Arch
; 456(1): 1-12, 2010 Jan.
Article
en En
| MEDLINE
| ID: mdl-19859732
ABSTRACT
This review discusses precursor lesions of endometrial and ovarian carcinoma with an emphasis on the unique molecular alterations that have led to the development of binary classification schemes for tumors of both the endometrium and ovary. While such a system is well established for endometrial carcinoma, only recently has a binary classification scheme been proposed for ovarian carcinoma. For both, the morphologic and molecular genetic-defining characteristics of their respective precursor lesions are described in detail. Furthermore, similarities and differences of the precursor lesions of specific tumors of these two genital tract organs are also addressed with a brief discussion of the clinical implications of their diagnosis.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neoplasias Ováricas
/
Lesiones Precancerosas
/
Neoplasias Endometriales
Límite:
Female
/
Humans
Idioma:
En
Revista:
Virchows Arch
Asunto de la revista:
BIOLOGIA MOLECULAR
/
PATOLOGIA
Año:
2010
Tipo del documento:
Article
País de afiliación:
Estados Unidos