Current management of antiphospholipid syndrome-related thrombosis.
Expert Rev Cardiovasc Ther
; 7(12): 1551-8, 2009 Dec.
Article
en En
| MEDLINE
| ID: mdl-19954317
ABSTRACT
Antiphospholipid syndrome (APS) is an acquired autoimmune disorder characterized by venous or arterial thrombosis, and recurrent pregnancy morbidity in the presence of antiphospholipid antibodies. Many physicians recommend a daily low dose of aspirin for primary thrombosis prevention in asymptomatic individuals with persistent antiphospholipid antibodies. However, recent data question the effectiveness of aspirin. For the secondary prevention of recurrent thrombosis, the most effective treatment is long-term anticoagulation. A moderate intensity of anticoagulation is recommended in the majority of APS patients. In cases of catastrophic APS, an aggressive therapy is highly recommended using immunosuppression and anticoagulants. This article will also review the experimental evidence of potential therapeutic approaches for the management of APS-related clinical events.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Trombosis
/
Síndrome Antifosfolípido
Límite:
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Expert Rev Cardiovasc Ther
Asunto de la revista:
ANGIOLOGIA
/
CARDIOLOGIA
/
TERAPEUTICA
Año:
2009
Tipo del documento:
Article
País de afiliación:
Argentina
Pais de publicación:
ENGLAND
/
ESCOCIA
/
GB
/
GREAT BRITAIN
/
INGLATERRA
/
REINO UNIDO
/
SCOTLAND
/
UK
/
UNITED KINGDOM