Innate immunity and gut-microbe mutualism in Drosophila.
Dev Comp Immunol
; 34(4): 369-76, 2010 Apr.
Article
en En
| MEDLINE
| ID: mdl-19958789
ABSTRACT
Metazoan guts face a wide variety of microorganisms upon exposure to the environment, including beneficial symbionts, non-symbionts, food-borne microbes and life-threatening pathogens. Recent evidence has shown that the innate immunity of gut epithelia, such as anti-microbial peptide- and reactive oxygen species-based immune systems, actively participate in gut-microbe homeostasis by shaping the commensal community while efficiently eliminating unwanted bacteria. Therefore, elucidation of the regulatory mechanism by which gut innate immunity occurs at the molecular level will provide a novel perspective of gut-microbe mutualisms as well as of gut diseases caused by alterations in the innate immunity.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Simbiosis
/
Tracto Gastrointestinal
/
Drosophila
/
Inmunidad Innata
Límite:
Animals
Idioma:
En
Revista:
Dev Comp Immunol
Año:
2010
Tipo del documento:
Article
País de afiliación:
Corea del Sur