A first-generation haplotype map of maize.
Science
; 326(5956): 1115-7, 2009 Nov 20.
Article
en En
| MEDLINE
| ID: mdl-19965431
ABSTRACT
Maize is an important crop species of high genetic diversity. We identified and genotyped several million sequence polymorphisms among 27 diverse maize inbred lines and discovered that the genome was characterized by highly divergent haplotypes and showed 10- to 30-fold variation in recombination rates. Most chromosomes have pericentromeric regions with highly suppressed recombination that appear to have influenced the effectiveness of selection during maize inbred development and may be a major component of heterosis. We found hundreds of selective sweeps and highly differentiated regions that probably contain loci that are key to geographic adaptation. This survey of genetic diversity provides a foundation for uniting breeding efforts across the world and for dissecting complex traits through genome-wide association studies.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Recombinación Genética
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Selección Genética
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Variación Genética
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Haplotipos
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Mapeo Cromosómico
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Genoma de Planta
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Zea mays
Idioma:
En
Revista:
Science
Año:
2009
Tipo del documento:
Article
País de afiliación:
Estados Unidos