Synthesis and antitumor activity of new dihydropyridine thioglycosides and their corresponding dehydrogenated forms.
Eur J Med Chem
; 45(3): 973-82, 2010 Mar.
Article
en En
| MEDLINE
| ID: mdl-20004044
ABSTRACT
A number of a new pyridine thioglycosides were synthesized via reaction of piperidinium salts of dihydropyridinethiones with 2,3,4,6-tetra-O-acetyl-alpha-D-gluco- and galactopyranosyl bromide. The antitumor activities of the synthesized compounds were evaluated utilizing two different human cell lines. Some of the tested compounds showed high inhibition of human cell lines. The detailed synthesis, spectroscopic data and antitumor activities for the synthesized compounds were reported.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Tioglicósidos
/
Dihidropiridinas
/
Antineoplásicos
Límite:
Animals
/
Humans
/
Male
Idioma:
En
Revista:
Eur J Med Chem
Año:
2010
Tipo del documento:
Article
País de afiliación:
Egipto