[The burden and outcomes of acute bronchiolitis among young children hospitalized in Israel].
Harefuah
; 148(11): 748-51, 795, 794, 2009 Nov.
Article
en He
| MEDLINE
| ID: mdl-20027974
ABSTRACT
BACKGROUND:
Acute bronchiolitis (AB) is a significant indication for hospitalization during the winter period. Underlying conditions increase risk for severe manifestations.AIMS:
To estimate the burden and outcomes of AB in northern Israel.METHODS:
A prospective study was performed between 1.12.2005 - 31.3.2006. Previously healthy children younger than 2 years of age, hospitalized with the diagnosis of AB, in three hospitals in northern Israel, were included in this study.RESULTS:
Overall, 465 children (93%) out of 500 children who were hospitalized due to AB and comprised 18% of all hospitalizations during the study period, were included. A pathogen was identified in 91% of cases. A single pathogen was identified in 243 (52%) cases; 2-4 pathogens were found in 176 (39%) children. Common pathogens were respiratory syncytial virus (RSV) and Rhinovirus in 346 (75%) and 129 (28%), of which 192 (41%) and 37 (8%) were sole pathogens respectively. Complete data were available for 390 (82%) children, of whom 78% were younger than 6 months. Patients were hospitalized for 4 +/- 4.4 days; 15 children were treated in intensive care. There was one mortality. An X-ray was performed in 94% of cases. Most children were treated with multiple regimens including intravenous fluids, O2 supplement, physiotherapy, bronchodilators, steroids and antibiotics. Bronchiolitis was attributed to 18% of hospitalizations. On a national scale, assuming that the policy of hospitalization is similar, 4100 children were hospitalized due to AB. This reflects 4% of all hospitalized children a year in Israel and attributing to 16,400 hospitalizations.CONCLUSIONS:
AB is associated with a huge burden, during a short period of the year, on pediatric departments, mainly attributed by infants younger than 6 months of age. The development of effective vaccine against RSV may significantly reduce the burden of morbidity.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Bronquiolitis
/
Niño Hospitalizado
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
Límite:
Humans
/
Infant
País/Región como asunto:
Asia
Idioma:
He
Revista:
Harefuah
Año:
2009
Tipo del documento:
Article
País de afiliación:
Israel