[Hymenoptera venom anaphylaxis and in-vitro diagnostic tools: new approaches to manage patients at high risk of a severe reaction]. / Allergie au venin d'hyménoptère et tests de laboratoires: de nouvelles approches pour la prise en charge des patients a haut risque de réaction sévère.

ABSTRACT

The consequences of Hymenoptera venom anaphylaxis are very severe but it is not obvious to predict which reactions will occur in one single patient when he is stung for the second time. For a couple of years, many new laboratory tests have been experimented and many studies published. CAST, BAT, WB, tryptase, sIgE and sIgG4 are the new valuable additional diagnostic tools that can help the decision to perform an immunotherapy or to discontinue this therapy after 3 years. The aim of our study was to determine which could be the profile of a desensitized patient and to screen for good candidates for venom immunotherapy.