Efficacy of continuous acyclovir infusion in neonatal herpes virus encephalitis.
Neuropediatrics
; 40(4): 199-200, 2009 Aug.
Article
en En
| MEDLINE
| ID: mdl-20135579
ABSTRACT
We have successfully eliminated herpes simplex virus-2 from the central nervous system in a case of neonatal herpes simplex virus encephalitis with a continuous acyclovir infusion. A male infant delivered from a healthy 22-year-old woman without genital or systemic herpes symptoms around delivery began to develop fever and intractable seizures. He was started on intermittent intravenous acyclovir (20 mg/kg every 8 h) based on the diagnosis of herpes encephalitis. The virus was not eliminated with intermittent acyclovir and vidarabine, while continuous acyclovir was ultimately effective in eliminating herpes simplex virus from his central nervous system. This report demonstrates the efficacy of continuous acyclovir infusion in neonatal herpes simplex virus encephalitis.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Antivirales
/
Aciclovir
/
Encefalitis por Herpes Simple
Límite:
Adult
/
Female
/
Humans
/
Male
/
Newborn
Idioma:
En
Revista:
Neuropediatrics
Año:
2009
Tipo del documento:
Article
País de afiliación:
Japón