A case of Paget's disease in hemodialysis.
Clin Nephrol
; 73(5): 403-7, 2010 May.
Article
en En
| MEDLINE
| ID: mdl-20420803
ABSTRACT
Paget's disease is the second most common bone disease after osteoporosis and causes an excessive bone turnover. Moreover, chronic kidney failure causes an impairment of bone mineral metabolism and electrolytes and PTH homeostasis. As far as we know, this is the first reported case of Paget's disease in a hemodialysis patient the patient was also affected by secondary hyperparathyroidism and was successfully treated with clodronate, cinacalcet and paracalcitol. The safety and efficacy of this combined therapy was periodically revised in a 12-month follow-up considering the common markers of bone turnover as well as the dosage of OPG, RANKL, IL-6 and MCSF, involved in the pathophysiology of Paget's disease.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Osteítis Deformante
/
Diálisis Renal
/
Hiperparatiroidismo Secundario
/
Fallo Renal Crónico
Tipo de estudio:
Diagnostic_studies
Límite:
Aged
/
Female
/
Humans
Idioma:
En
Revista:
Clin Nephrol
Año:
2010
Tipo del documento:
Article
País de afiliación:
Italia