[Pathophysiology of immune thrombocytopenia]. / Physiopathologie du purpura thrombopénique immunologique.

ABSTRACT

Immune thrombocytopenia is an autoimmune disease characterized by a peripheral destruction of platelets. B lymphocytes play a key role but pathogenesis is more complex, involving humoral and cellular immunity associated with an inappropriate platelet production. In this article, we review the different pathogenic pathways, leading to new therapeutic strategies.