Immune factors in human embryo culture and their significance.
Medicina (Kaunas)
; 46(4): 233-9, 2010.
Article
en En
| MEDLINE
| ID: mdl-20571290
ABSTRACT
There is increasing evidence that human development before implantation is regulated by embryonically and maternally derived growth factors. The "regulators" of embryonic origin such as soluble human leukocyte antigen G, platelet-activating factor, Th1/Th2 cytokines, insulin-like growth factor, epidermal growth factor, transforming growth factor alpha, colony-stimulating factor, platelet-derived growth factor may be used as indicators of embryo viability and implantation potential. The data prove the influence of growth factors on the development and growth of preimplantation embryos. Though there is a lot of research in the field of biomarkers during folliculogenesis and maternal-fetal interface, only few of them deal with regulators derived from embryonic cells to the cultivation medium. The aim of our study was to summarize the research dealing with immune markers produced by embryos in vitro and to estimate their impact on the cell growth, viability and implantation potential.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Implantación del Embrión
/
Somatomedinas
/
Factor de Activación Plaquetaria
/
Factores de Crecimiento Transformadores
/
Fertilización In Vitro
/
Desarrollo Embrionario
Límite:
Animals
/
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Medicina (Kaunas)
Asunto de la revista:
MEDICINA
Año:
2010
Tipo del documento:
Article
País de afiliación:
Lituania