Genotyping of Porcine teschovirus from nervous tissue of pigs with and without polioencephalomyelitis in Indiana.
J Vet Diagn Invest
; 22(4): 594-7, 2010 Jul.
Article
en En
| MEDLINE
| ID: mdl-20622231
ABSTRACT
Porcine teschovirus (PTV) was isolated in cell culture and/or demonstrated by polymerase chain reaction in samples of brain and/or spinal cord in pigs in Indiana during the 2002-2007 period. Testing was initiated on pigs originating from populations exhibiting nervous clinical disease and/or pigs with microscopic lesions in central nervous tissues, indicating viral encephalitis and/or myelitis. Virus was demonstrated in pigs with and without lesions as well as with and without nervous clinical disease. Nucleotide sequence analysis of the 5'-nontranslated region of the viral genome revealed that these isolates had low-level genetic heterogeneity but were homologous to porcine PTV serotype 1 (PTV-1). These findings indicate that low-to-moderate virulence strains of PTV with some homology to PTV-1 are endemic in many swineherds of Indiana and are associated with subclinical and clinical nervous disease in weaned pigs.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Médula Espinal
/
Enfermedades de los Porcinos
/
Encéfalo
/
Infecciones por Picornaviridae
/
Encefalomielitis
/
Teschovirus
Límite:
Animals
País/Región como asunto:
America do norte
Idioma:
En
Revista:
J Vet Diagn Invest
Asunto de la revista:
MEDICINA VETERINARIA
Año:
2010
Tipo del documento:
Article
País de afiliación:
Estados Unidos