Synthesis, solvatochromaticity and bioactivities of some transition metal complexes with 2-(R-benzylideneamino)-pyridin-3-ol Schiff base derivatives.
Spectrochim Acta A Mol Biomol Spectrosc
; 77(2): 359-66, 2010 Oct 01.
Article
en En
| MEDLINE
| ID: mdl-20638329
ABSTRACT
New four Schiff bases are prepared by condensation of 2-amino-pyridin-3-ol with 3, 4-dihydroxy-benzaldehyde (I), 2-hydroxybenzaldehyde (II), 5-bromo-2-hydroxybenzaldehyde (III), and 4-dimethylaminobenzaldehyde (IV). The structures of these compounds are characterized based on elemental analyses (C. H. N), IR and (1)H NMR. Also, the electronic absorption spectra are recorded in organic solvents of different polarity. The solvents are selected to be covered a wide range of parameters (refractive index, dielectric constant and hydrogen bonding capacity). The UV-vis absorption spectra of Schiff base compounds are investigated in aqueous buffer solutions of varying pH and utilized for the determination of ionization constant, pK(a) and activation free energy, DeltaG(*) of the ionization process. The biological activity against bacterial species and fungi as microorganisms representing different microbial categories such as (two Gram-negative bacteria, Eschericha coli and Agrobacterium sp.),three Gram-positive bacteria (Staphylococcus aureus, Bacillus subtlus and Bacillus megatherium), yeast (Candida albicans), and fungi (Aspergillus niger) were studied.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Piridinas
/
Bases de Schiff
/
Solventes
/
Benzaldehídos
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Elementos de Transición
Idioma:
En
Revista:
Spectrochim Acta A Mol Biomol Spectrosc
Asunto de la revista:
BIOLOGIA MOLECULAR
Año:
2010
Tipo del documento:
Article
País de afiliación:
Egipto
Pais de publicación:
ENGLAND
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ESCOCIA
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GB
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GREAT BRITAIN
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INGLATERRA
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REINO UNIDO
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SCOTLAND
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UK
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UNITED KINGDOM