Orange but not apple juice enhances ferrous fumarate absorption in small children.
J Pediatr Gastroenterol Nutr
; 50(5): 545-50, 2010 May.
Article
en En
| MEDLINE
| ID: mdl-20639713
ABSTRACT
OBJECTIVE:
Ferrous fumarate is a common, inexpensive iron form increasingly used instead of ferrous sulfate as a food iron supplement. However, few data exist as to whether juices enhance iron absorption from ferrous fumarate. SUBJECTS ANDMETHODS:
We studied 21 children, ages 4.0 to 7.9 years using a randomized crossover design. Subjects consumed a small meal including a muffin containing 4 mg Fe as ferrous fumarate and either apple (no ascorbic acid) or orange juice (25 mg ascorbic acid). They were separately given a reference dose of Fe (ferrous sulfate) with ascorbic acid.RESULTS:
Iron absorption increased from 5.5% +/- 0.7% to 8.2% +/- 1.2%, P < 0.001 from the muffins given with orange juice compared with muffins given with apple juice. The absorption of ferrous fumarate given with orange juice and enhancement of absorption by the presence of juice were significantly positively related to height, weight, and age (P < 0.01 for each). Although iron absorption from ferrous fumarate given with apple juice was significantly inversely associated with the (log transformed) serum ferritin, the difference in absorption between juice types was not (P > 0.9).CONCLUSIONS:
These data demonstrate an overall benefit to iron absorption from ferrous fumarate provided with orange juice. The effect was age related such that in children older than 6 years of age, there was a nearly 2-fold increase in iron absorption from ferrous fumarate given with orange juice.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Bebidas
/
Compuestos Ferrosos
/
Malus
/
Preparaciones de Plantas
/
Citrus sinensis
/
Absorción Intestinal
/
Hierro
Tipo de estudio:
Clinical_trials
Límite:
Child
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Child, preschool
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
J Pediatr Gastroenterol Nutr
Año:
2010
Tipo del documento:
Article
País de afiliación:
Estados Unidos