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[An elderly advanced breast cancer with a good response to anastrozole].
Matsui, Koshi; Tazawa, Kenichi; Karato, Michiyo; Nagata, Takuya; Shimada, Yutaka; Tsukada, Kazuhiro.
Afiliación
  • Matsui K; Dept. of Surgery and Science, Graduate School of Medicine and Pharmaceutical Sciences for Research, University of Toyama.
Gan To Kagaku Ryoho ; 37(8): 1557-60, 2010 Aug.
Article en Ja | MEDLINE | ID: mdl-20716886
The patient was an 86-year-old woman. In December 2005, she became aware of a tumor in her right breast at the nipple, gradually increasing in size and bleeding, and visited our department in April 2006. Roughly 3.5 cm in size, the tumor had a prominent large skin surface, bled profusely, and a dark red-colored was found at the E area of the right breast. Ultrasonography and mammography revealed that the tumor had invaded the skin and pectoralis major muscle (T4b). Core needle biopsy examination indicated invasive breast cancer (pap-tub), ER(+), PgR(+), HER2(3+). Chest CT scan and bone scintigraphy revealed swollen changes at the right axillary lymph nodes and osteoblastic changes in the 7th thoracic vertebra. We started anastrozole 1mg/day treatment. Tumor blood loss after one month was confirmed. After six months, the primary tumor size was reduced to 2 cm and the axillary lymph nodes disappeared. Administration continued about three years, and the tumor showed only the scar-like changes, and was unclear from ultrasonography (cPR). We report the long-term effect of aromatase inhibitor for elderly breast cancer patients without operation.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Triazoles / Neoplasias de la Mama / Antineoplásicos Hormonales / Inhibidores de la Aromatasa / Nitrilos Tipo de estudio: Diagnostic_studies Límite: Aged80 / Female / Humans Idioma: Ja Revista: Gan To Kagaku Ryoho Año: 2010 Tipo del documento: Article Pais de publicación: Japón
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Triazoles / Neoplasias de la Mama / Antineoplásicos Hormonales / Inhibidores de la Aromatasa / Nitrilos Tipo de estudio: Diagnostic_studies Límite: Aged80 / Female / Humans Idioma: Ja Revista: Gan To Kagaku Ryoho Año: 2010 Tipo del documento: Article Pais de publicación: Japón