Glycemic response to stress stimulation by ether exposure in adrenalectomized rats.
Pharmacol Biochem Behav
; 37(3): 399-403, 1990 Nov.
Article
en En
| MEDLINE
| ID: mdl-2087480
ABSTRACT
Stress was induced by short-term ether exposure (2 min) and tail vein puncture in normal (SO), adrenodemedullated (ADM), and adrenalectomized (ADR) rats. In ADM and SO rats stress provoked a significant hyperglycemic response with no change in plasma insulin levels. In ADR rats, on the other hand, the hyperglycemic response was not present. Actually, a significant rapid decrease in blood glucose, plasma insulin and hepatic glycogen content was observed. When the hypoglycemic effect of stress was prevented by glucose injection into ADR rats the decrease in plasma insulin and hepatic glycogen was not observed. The data suggest that the fall in plasma insulin and hepatic glycogen content observed in ADR animals result from an activation of the sympathetic nervous system induced by the decrease in blood glucose.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Estrés Fisiológico
/
Glucemia
/
Adrenalectomía
/
Éter
Límite:
Animals
Idioma:
En
Revista:
Pharmacol Biochem Behav
Año:
1990
Tipo del documento:
Article
País de afiliación:
Brasil