Cinnamic esters of acyclovir-synthesis and biological activity.
Nucleosides Nucleotides Nucleic Acids
; 29(10): 760-7, 2010 Oct.
Article
en En
| MEDLINE
| ID: mdl-20924957
ABSTRACT
In the present study we have synthesized esters of acyclovir with cinnamic acids (p-coumaric, ferulic, and sinapic acids) and evaluated them for their antiviral and antioxidant potential. The antiviral activity of the newly synthesized compounds has been tested against human herpes virus 1 (HSV-1) in vitro. The results indicate that none of the synthesized compounds inhibits the tested virus strain. The antioxidant properties have been studied using 2,2-diphenyl-1-picrylhydrazyl (DPPH)* test.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Antivirales
/
Aciclovir
/
Cinamatos
/
Antioxidantes
Límite:
Animals
Idioma:
En
Revista:
Nucleosides Nucleotides Nucleic Acids
Asunto de la revista:
BIOQUIMICA
Año:
2010
Tipo del documento:
Article
País de afiliación:
Bulgaria