Suboptimal persistence with inhaled corticosteroid monotherapy among children with persistent asthma in the UK.
Prim Care Respir J
; 20(1): 97-101, 2011 Mar.
Article
en En
| MEDLINE
| ID: mdl-20936252
ABSTRACT
BACKGROUND:
Long-term studies indicate that adherence to asthma controller therapy decreases over time, and persistence with therapy may be poor.METHODS:
This primary care database study assessed persistence with therapy over one year after first prescription of inhaled corticosteroid (ICS) for children aged 2-14 years with a diagnosis of asthma. Children with intermittent asthma were excluded. Discontinuation was defined as no ICS prescription during the last three months of the follow-up year.RESULTS:
2220 of 7375 children receiving a first prescription for ICS had persistent asthma. Mean (±SD) age was 7.3 (±3.8) years; 59.5% were male. A total of 745 (33.6%) continued initial ICS, 133 (6.0%) received add-on therapy, 150 (6.8%) switched to another asthma therapy, and 1192 (53.7%) discontinued therapy. These percentages were similar for children aged 2-5 or 6-14 years.CONCLUSION:
Persistence with first-time ICS monotherapy is poor among children with persistent asthma.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Asma
/
Cooperación del Paciente
/
Corticoesteroides
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
Límite:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
País/Región como asunto:
Europa
Idioma:
En
Revista:
Prim Care Respir J
Año:
2011
Tipo del documento:
Article
País de afiliación:
Estados Unidos